Gène affecté: RHO
Transmission:  Autosomal Dominant
Mutation: CanFam3.1    20    g.5637394G>C    c.11C>G
Lien OMIA:  001346-9615
 
Races appropriées pour les tests : Mastiff Anglais, Bullmastiff

Références:
Kijas JW, Cideciyan AV, Aleman TS, Pianta MJ, Pearce-Kelling SE, Miller BJ, Jacobson SG, Aguirre GD, Acland GM. Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa. Proc Natl Acad Sci U S A. 2002 Apr 30; 99(9):6328-33. [PubMed: 11972042]
Kijas JW, Miller BJ, Pearce-Kelling SE, Aguirre GD, Acland GM. Canine models of ocular disease: outcross breedings define a dominant disorder present in the English mastiff and bull mastiff dog breeds. J Hered. 2003 Jan-Feb; 94(1):27-30. [PubMed: 12692159]