Affected gene: RHO
Inheritance: Autosomal Recessive
Mutation: CanFam3.1 20 g.5637394G>C c.11C>G
OMIA link: 001346-9615Appropriate breeds for testing: Mastiff , Bullmastiff
References:
Kijas JW, Cideciyan AV, Aleman TS, Pianta MJ, Pearce-Kelling SE, Miller BJ, Jacobson SG, Aguirre GD, Acland GM. Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa. Proc Natl Acad Sci U S A. 2002 Apr 30; 99(9):6328-33. [PubMed: 11972042]
Kijas JW, Miller BJ, Pearce-Kelling SE, Aguirre GD, Acland GM. Canine models of ocular disease: outcross breedings define a dominant disorder present in the English mastiff and bull mastiff dog breeds. J Hered. 2003 Jan-Feb; 94(1):27-30. [PubMed: 12692159]
Progressive Retinal Atrophy (PRA-D), RHO Gene- Mastiff Type
5 tests et + 55$ch.
After your samples are received at the laboratory, please allow 10 to 15 business days for your results to be sent.