Affected gene: USP31
Inheritance: Complex
Mutation: CanFam3.1 
 
Mutation: CanFam2
 
AOD1 USP31 Chr6.25681850 T>G
 
AOD2 USP31 Chr6.25714052 A>G
 
AOD3 HS3ST2 Chr6.25819273 A>C
 
AOD4 RBBP6 Chr6.24500625 G>T
OMIA link:
 

 
Suitable breeds for testing: Border Collie
 

 
Symptoms:
Hearing loss progresses gradually, affecting the dog’s ability to respond to distant or whistle commands, which is essential for its role as a working herding dog.
 
Deafness is generally not congenital but develops in adulthood, often going unnoticed until it begins to interfere with the dog’s work.
 
Late recognition can negatively impact the dog’s training and quality of life.