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Cycling Neutropenia (CN, AP3B1 Gene)

Other Names: Cyclic Hematopoiesis, Gray Collie Syndrome
Affected Gene: AP3B1
Transmission: Autosomal recessive
Mutation: CanFam3.1 chr3 g.28663129_28663130insA c.2407_2408insA


Breeds Recommended for Testing: Collie, Smooth Coat Collie, Rough Coat Collie


References:

Benson KF, Li FQ, Person RE, Albani D, Duan Z, Wechsler, Meade-White K, Williams K, Acland GM, Niemeyer G, Lothrop CD, Horwitz M. Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase. Nat Genet. 2003 Sep;35(1):90-6.

Lothrop CD Jr, Coulson PA, Nolan HL, Cole B, Jones JB, Sanders WL. Cyclic hormonogenesis in gray collie dogs: interactions of hematopoietic and endocrine systems. Endocrinology. 1987 Mar;120(3):1027-32.

Cycling Neutropenia (CN, AP3B1 Gene)

C$65.00Price

5 tests et + 55$ch.

Quantity

 Après la réception de vos échantillons au laboratoire, veuillez prévoir un délai de 10 à 15 jours ouvrables pour l’envoi de vos résultats.

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