Other Names: Christmas disease, Factor IX deficiency
In English: Hemophilia B (F9) - Cairn Terrier
Affected Gene: F9
Transmission: Recessive, X-linked
Mutation: CanFam3.1 X g.109532018G>A c.1253G>A
In X-linked recessive genetic diseases, the following rules apply:
  
For a recessive disease, males are affected (at risk of developing the disease) even with only one copy of the mutation.
  
Males do not pass on their X chromosome to their sons.
  
All females of an affected male will inherit the mutant gene.
  
Females that are carriers have a 50% chance of passing the mutant gene to both sons and daughters.
OMIA Link: 000438-9615
Breeds Recommended for Testing: Cairn Terrier

References:
Evans, J.P., Brinkhous, K.M., Brayer, G.D., Reisner, H.M., High, K.A.
Canine hemophilia B resulting from a point mutation with unusual consequences.
Proc Natl Acad Sci U S A. 1989 Dec; 86(24):10095-9. PubMed: 2481310