Affected Gene: ADAMTS10
Transmission: Autosomal Recessive
Mutation: CanFam3.1 20 g.53096339C>T c.1981G>A
OMIA Link: 001870-9615

Breeds Recommended for Testing: Beagle, Miniature Pinscher

References:
Gelatt KN, Peiffer RL Jr, Gwin RM, Gum GG, Williams LW. Clinical manifestations of inherited glaucoma in the Beagle.
Invest Ophthalmol Vis Sci. 1977 Dec;16(12):1135-42.
Kuchtey J, Kunkel J, Esson D, Sapienza JS, Ward DA, Plummer CE, Gelatt KN, Kuchtey RW. Screening ADAMTS10 in Dog Populations Supports Gly661Arg as the Glaucoma-Causing Variant in Beagles.
Invest Ophthalmol Vis Sci. 2013 Mar 13;54(3):1881-6.
Kuchtey J, Olson LM, Rinkoski T, MacKay EO, Iverson TM, Gelatt KN, Haines JL, Kuchtey RW. Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open-angle glaucoma.
PLoS Genet. 2011 Feb;7(2):e1001306.